What are the symptoms of smallpox?
Initial symptoms of smallpox include high fever, fatigue, and head and back aches. A characteristic rash, most prominent on the face, arms, and legs, follows in two to three days. The rash starts with flat red lesions that evolve at the same rate. Lesions become pus-filled and begin to crust early in the second week. Scabs develop and then separate and fall off after three to four weeks. The majority of patients with smallpox recover, but death occurs in up to 30% of cases.

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1. What is smallpox?
2. When was the last case of smallpox reported in the United States?
3. What is the incubation period for smallpox?
4. What are the symptoms of smallpox?
5. How is smallpox spread?
6. Is a smallpox vaccine available?
7. Is there a treatment for smallpox?